New Perspectives in Anti-Inflammatory Therapies
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New Perspectives in Anti-Inflammatory Therapies description from Lippincott Williams & Wilkins
This volume explores the potential for developing new antiarthritic drugs that act on cytokines, degradative enzymes, and lipid mediators involved in inflammation. The contributors present key findings on the role of interleukins, colony stimulating factors, cachectin, leukotriene B4, and platelet-activating factor in the inflammatory process and offer promising leads for developing specific antagonists to these substances. Several chapters explore new approaches to developing drugs to control the degradative processes occurring in osteoarthritis. Other studies presented suggest that drugs that act on lipid mediators may be of value in treating psoriasis, asthma, myocardial ischemia, and inflammatory bowel disease. The book also assesses the efficacy of several antirheumatic agents that are now undergoing clinical and preclinical testing, such as cyclosporine, sulphasalazine, gamma-interferon, and organoselenium compounds.
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